608141-41-9

Formula

Seres Product Name: AESTA

Sinica alias: (s) -2- [1- (III-Ethoxy-IV-IV-methoxyphenyl) -2, methaneulfonylethyl] -4, acetylaminoisoisoiso, 1,3 -Diketone

Anglicus Product Name: Apremlast

CAS # 608141-41-9

Molecular Formula: C22H24N2O7s

Molecular pondus: 460,5

Species et proprietates: Off-album pulveris

608141-41-9 est pro PSoriatici arthritis medicamento, PSORIASIS et PSoriatic arthritis medicamento.

Usus: Apremlast est oris, selectivam phosphodiisterstere IV (Pde4) inhibitor inhibitor per American Company Celgene, cum commercia nomine Otezla. Hoc medicamento est prima et tantum FDA-probatus medicamento ad TABULA-genus argentum. Pde4 inhibitor ad curatio de PSORIASIS, ad curatio ad adulta aegris cum moderari ad gravibus plaque PSORIASIS (Plaque PSORIASIS), qui idoneam phototherapy et systemic Lorem.

CAS 608141-41-9, a unique eget identifier, represents compositis et crescente interest in utroque academic et industriae investigationis. Hoc articulum DENDES in suum eget proprietatibus, synthesim modi, applications, salus considerations, et futurae spes, extollit significationem cas 608141-41-9 per diverse agris.

Eget identitatem et fabrica features

CAS 608141-41-9 correspondet ad structuram universa universa organicum molecule, propria per fusi heterocyclic compage. Analytica techniques ut NMR et Missam spectrometry confirmare suum mocecular formula ut c₁₅h₁₈n₂o₃s. In praesentia de Sulfonamide et aromaticum moeties in cas 608141-41-9 suggerit potential reactivity in electrophilic substitutione et hydrogenii vinculum interactiones, faciens illud a versatile candidatum ad derivatization.

Synthesis et Optimization

In synthesis Cas 608141-41-9 typically involves a multi-gradus protocol incipiens a commercium available precursors. A key medium, II-aminothiophenol, subit sequentem alkylation et cyclization in praesentia de Ludovicus acidum Catalyst. Recens progressiones sunt melius cede of CAS 608141-41-9 ad> LXXV% per optimizing solvendo systems (E.G., DMF / aquae mixturis) et reactionem temperaturis (80-100 ° C). Inquisitores commendandam partes purificationis per columna chromatography segregare cas 608141-41-9 in excelsum puritatis (> XCVIII%).

Industrial et Pharmaceutical Applications

CAS 608141-41-9 habet garnered operam ad suum dual functionality ut corrosio inhibitor et bioactive agente. In materiae scientiae, formities continet 0.5-2% cas 608141-41-9 demonstrabo eximia efficacia in protegens ferro alloys sub acidic conditionibus. Interim, PROMPERMINIBUS pharmacological Studies revelare quod CAS 608141-41-9 exhibet modica antimicrobial actio contra gram, positivum Bacteria (mic, XXXII μg / ml), positioning ut a scafflold pro antibiotic progressionem.

Salus et regulatory considerations

Tractantem cas 608141-41-9 postulat adhaesione stricte salutem protocols. Acutus toxicity assays referatur sicut genus IV (LD₅₀> D mg / kg in talpas), sed longum differentur nuditate potest inducere dermal sensitization. Regulatory corpora ut EPA et ECHA Mandate propriis Labeling et arbitrio Cas 608141-41-9 ad mitigare environmental metus. Workplace Nuditate fines sunt set ad V mg / m³ (VIII-hora twa).

Future Research directiones

In versatility of CAS 608141-41-9 opens aditus ad innovation. Computational modeling potuit praedicere novel derivationes cum auctus proprietatibus, dum viridi elit accedit ad redigendum in adipiscing vestigium eius synthesis. Collaborative nisus ad explorandum Cas 608141-41-9 in Nanotechnology (E.G., ut Ligand pro metallum-organicum frameworks) iam citatus.

Conclusio

CAS 608141-41-9 exemplificat intersection of chemica et practicality. Et unique structuram, scalable synthesis, et multifunctional applications underscore sua pretii in modern scientia. Ut research evolves, cas 608141-41-9 est Poised ludere a Pivotal Partes in addressing challenges vndique a industriae sustainability ad publicam salutem.